MacKinnon Group

Organic Chemistry at the University of Regina

The MacKinnon Group is housed in the Department of Chemistry and Biochemistry at the University of Regina in Regina, Saskatchewan, Canada

About Dr. Marc MacKinnon

Assistant Professor

Marc was born and raised in Kitchener, Ontario, Canada. He attended Wilfrid Laurier University, where he worked as an undergraduate researcher in the lab of Dr. Ken Maly. After his BSc, he moved to St. John's, Newfoundland, where he attended Memorial University for his Master's and Ph.D. studies in the lab of Dr. Graham Bodwell. While in Newfoundland, Marc learned how to be an organic chemist working in the areas of cyclophanes and designed 𝜋-systems. Marc then moved to Hamilton, Ontario, to work at McMaster University in the lab of Dr. Jakob Magolan, which is housed in the Michael G. DeGroote Institute for Infectious Disease Research. His postdoctoral research allowed him to broaden his research areas to include medicinal chemistry with a focus on developing new antibiotic molecules.

Scholarly Work

Research Articles

5. QSAR models reveal new EPAC-selective allosteric modulators

H. Mohamed, H. Shao, M. Akimoto, P. Darveau, M. R. MacKinnon, J. Magolan, G. Melancini*

RSC Chem. Biol. 2022 3, 1230-1239. https://doi.org/10.1039/D2CB00106C

4. Genetic and Chemical Screening Reveals Targets and Compounds to Potentiate Gram-Positive Antibiotics against Gram-Negative Bacteria

K. Klobuchar, E. Jardine, M. A. Farha, M. R. MacKinnon, M. Fragis, B. Nkonge, T. Bhando, L. Borrillo, C. N. Tsai, J. W. Johnson, B. K. Coombes, J. Magolan, E. D. Brown*

ACS Infect. Dis. 2022, 8 (10), 2187-2197. https://doi.org/10.1021/acsinfecdis.2c00357

3. Synthesis of a π-Extended Azacorannulenophane Enabled by Strain-Induced 1,3-Dipolar Cycloaddition (Cyclophanes - Hot Paper)

X. Zhang, M. R. MacKinnon, G. J. Bodwell, S. Ito*

Angew. Chem. Int. Ed. 2022 61. https://doi.org/10.1002/anie.202116585

2. Sodium sulfide on coal fly ash (Na2S/CFA) as a reagent for the synthesis of dithia[3.3]cyclophanes

M. R. MacKinnon, R. N. Warren, S. Brake, B. Zhang, L. Wang, G. J. Bodwell*

Can. J. Chem. 2020 98 (6), 322-326. https://doi.org/10.1139/cjc-2020-0041

1. A C-Pyrenyl Poly(methylenephosphine): Oxidation “Turns On” Blue Photoluminescence in Solution and the Solid State

B. W. Rawe, C. M. Brown, M. R. MacKinnon, B. O. Patrick, G. J. Bodwell, D. P. Gates*

Organometallics 2017 36 (14), 2520-2526. https://doi.org/10.1021/acs.organomet.6b00880

Get in Touch

Department of Chemistry and Biochemistry
University of Regina

marc.mackinnon[at]uregina[dot]ca